HomeContactEndoscopesHomeFujifilmHoyaKarl StorzOlympusPanasonicRichard WolfSolosManufacturers infoFujifilm endoscopesReducing patient discomfort and enhancing imaging precision. Industry-leading Fujifilm innovations include the transnasal endoscope and double-balloon endoscope. More »Fujinon EVE 590 seriesWith the pioneering 4400 endoscopy system, Fujinon is already meeting tomorrow’s standards in endoscopy today. More »Fujifilm endoscopes 600 seriesThe leading-edge high resolution endoscopes, equipped with over megapixel customised CMOS image sensor, realize advanced observation and diagnosis. More »Transnasal EndoscopyIn order to counter increasing cost pressure in modern endoscopy, Fujifilm has developed a complete product range for transnasal endoscopy (TNE).  More »Diagnostic performance of narrowed spectrum endoscopy, autofluorescence imaging, and confocal laser endomicroscopy for optical diagnosis of colonic polyps: a meta-analysisJanuary 4, 2014UncategorizedBackgroundNovel endoscopic technologies could allow optical diagnosis and resection of colonic polyps without histopathological testing. Our aim was to establish the sensitivity, specificity, and real-time negative predictive value of three types of narrowed spectrum endoscopy (narrow-band imaging [NBI], image-enhanced endoscopy [i-scan], and Fujinon intelligent chromoendoscopy [FICE]), confocal laser endomicroscopy (CLE), and autofluorescence imaging for differentiation between neoplastic and non-neoplastic colonic lesions.MethodsWe identified relevant studies through a search of Medline, Embase, PubMed, and the Cochrane Library. Clinical trials and observational studies were eligible for inclusion when the diagnostic performance of NBI, i-scan, FICE, autofluorescence imaging, or CLE had been assessed for differentiation, with histopathology as the reference standard, and for which a 2 × 2 contingency table of lesion diagnosis could be constructed. We did a random-effects bivariate meta-analysis using a non-linear mixed model approach to calculate summary estimates of sensitivity and specificity, and plotted estimates in a summary receiver-operating characteristic curve.FindingsWe included 91 studies in our analysis: 56 were of NBI, ten of i-scan, 14 of FICE, 11 of CLE, and 11 of autofluorescence imaging (more than one of the investigated modalities assessed in eight studies). For NBI, overall sensitivity was 91·0% (95% CI 88·6—93·0), specificity 85·6% (81·3—89·0), and real-time negative predictive value 82·5% (75·4—87·9). For i-scan, overall sensitivity was 89·3% (83·3—93·3), specificity 88·2% (80·3—93·2), and real-time negative predictive value 86·5% (78·0—92·1). For FICE, overall sensitivity was 91·8% (87·1—94·9), specificity 83·5% (77·2—88·3), and real-time negative predictive value 83·7% (77·5—88·4). For autofluorescence imaging, overall sensitivity was 86·7% (79·5—91·6), specificity 65·9% (50·9—78·2), and real-time negative predictive value 81·5% (54·0—94·3). For CLE, overall se