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    • 标题:
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    • 关键字:
    • primer selection software tool PCR software Oligo 7 program batch p 
    • 描述:
    • OLIGO performs a range of functions for researchers in PCR and related technologies, enables to desi 
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    oligo.net

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    网站首页快照(纯文字版)
    抓取时间:2013年11月04日 13:15:05
    网址:http://www.oligo.net/
    标题:Primer Design with Oligo Primer Analysis Software v. 7
    关键字:primer selection software tool, PCR software, Oligo 7 program, batch processing PCR primer analysis, sequencing primers
    描述:OLIGO performs a range of functions for researchers in PCR and related technologies, enables to design consensus, multiplex and degenerate primers. Reverse translation, restriction enzyme and open rea
    主体:
    According to  Soft-Go,  independent reviewers, Oligo exceeds quality standards.
    Oligo 7 New Features
    OLIGO Primer Analysis Software is the essential tool for designing and analyzing sequencing and PCR primers, synthetic genes, and various kinds of probes including siRNA and molecular beacons. 
    Based on the most up-to date nearest neighbor thermodynamic data, Oligo's search algorithms find optimal primers for PCR, including TaqMan, highly multiplexed, consensus or degenerate primers.  Multiple file batch processing is possible. It is also an invaluable tool for site directed mutagenesis. 
    For each primer or primer pair, Oligo's various analysis windows show a multitude of useful data, such as DNA and RNA secondary structure, dimer formation, false priming and homology, internal stability, composition and physical properties.  With Oligo you can analyze open reading frames down to predicted molecular weight and pKa of proteins, and search for restriction enzyme sites, not only in DNA but also in reverse-translated proteins.
    The first version of the software appeared on the market in 1989. It went through several modifications, and the last one, the change from version 6 to 7, was the most comprehensive. Oligo 7 can automatically select multiplex primers, process sequence files in batch modes, automatically design PCR primers to cover multiple DNA regions in just one search and automatically find primer/probe sets for real time PCR or finds nested primers sets. Oligo search protocols (scoring system) may be customized in detail, so you may optimize the results according to your specific needs. 
    Oligo runs on  Macintosh and Windows and it may be downloaded from this site. Click on the Tutorials link above to see Oligo 7 general overview and the major windows screen designs.
    OLIGO's comprehensive functionality matches several other commercial primer design applications put together, so you can design probes for high throughput analysis, multiplex them or focus on one set of primers/probes and optimize it for a new, not yet published application.
    Unlike other vendors who license software for a certain period of time, Oligo is supported as long as you use it. We still help customers who use Oligo 5, released in the mid 90's. Our pricing and ordering form are given on the Ordering page.
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